Examination Of Vitamin D Receptor (Vdr) Protein Levels In Type Ii Diabetes Mellitus Patients In Makassar

Abstract

Type II diabetes mellitus is a disease characterized by hyperglycemia resulting from the body's resistance to the effects of insulin produced by pancreatic cells. Type II diabetes mellitus can be associated with a deficiency of Vitamin D receptors (VDR). This study aims to determine the levels of Vitamin D receptor (VDR) protein in type II diabetes mellitus patients. This type of research is a type of laboratory observation research. This study used the serum of 15 samples of type II diabetes mellitus patients and then measured the levels of vitamin D receptor protein (VDR) using the ELISA method (Enzyme linked Immunosorbent Assay). The results showed that there was a decrease in vitamin D receptor (VDR) levels in 12 samples (60%). So it can be concluded that the decrease in vitamin D receptor (VDR) levels in type II diabetes mellitus patients did not show a significant difference (p = 0.386) and (p = 0.710).